Other Research Innovations

Fragrance preparation by microbial fermentation


Microbial fermentation technology is the process of making or producing certain products by biotransformation using microbial cells. Although the history of the preparation of spices by microbial fermentation is not very long, it has shown strong vitality and broad market prospect because of its advantages such as mild conditions, wide open source and renewable raw materials, high specificity and selectivity, simple process and environmental friendliness. Bolton Group has a variety of different specifications of fermenter, can meet the small test, pilot test and scale up production and other different requirements, and has years of production technology precipitation and experience accumulation.


Perfume preparation by enzyme catalysis


Bioenzyme catalysis technology is characterized by high catalytic efficiency, strong specificity, mild reaction conditions and environmental friendliness. It has been widely used in flavor and fragrance industry of our company. In addition, it is also involved in some food additives, daily chemicals, cosmetics and pharmaceutical intermediates industries. Non-aqueous enzymatic reactions have been used by us to catalyze a variety of spices. Bolton Group has a variety of different specifications of enzymatic hydrolysis tank, can meet the production needs of different specifications.


Perfume preparation by resting cell catalysis


Resting cell catalysis is a process in which one or several groups of a compound are transformed into another substance by the use of cultured cell bacteria re-suspended in a buffer solution. Resting cell catalysis technology has become an important technique used by Burton Group in the production of a variety of flavors and fragrances.


Molecular biological platform and strain breeding technology for aroma preparation


Botton Fragrance has established a molecular biology platform, which can use various existing technical means of genetic engineering to randomly introduce mutations into target genes at a low rate or recombine target genes, so as to obtain the mutant library, and then screen optimized enzymes with certain screening methods to meet the production needs.


Strain breeding technology can not only improve the yield of target products, greatly reduce production costs, improve economic benefits, but also simplify the process, reduce by-products, increase the yield, change the composition of effective components, and can be used to develop new products. The technology of strain selection and breeding provides the technical guarantee for our microbial fermentation technology.


Green synthetic chemical technology for preparation of spices


Through the synthesis of new, non-toxic harmless, high selective catalyst for green synthesis, applied to the spices by green solvent and the choice of solvent green recycling, not only can obtain high quality synthetic spices products applied to the company's essence formula, also reduced the pollution to the environment, to strengthen the social responsibility.


Synthesis of chiral fragrances


High purity chiral fragrance has a stronger aroma, less amount can achieve better results, more in line with the development requirements of green environmental protection. By synthesizing a range of chiral flavoring ingredients, Burton Group uses them in our flavoring formulations to make the flavoring products of higher quality and more competitive.


Synthesis of novel flavor compounds


Modern separation and analysis techniques were used to isolate new flavor compounds with good application value from natural plants, identify their chemical structures, and study their synthetic routes and methods. Because of low content of these compounds in plants, the price is expensive, not has industrial application value, through modern green chemical synthesis approach to production, can reduce cost, make the new type of raw material has the application value, greatly enriches our essence of the use of raw materials, flavouring division can allocate more different style, closer to the nature of the essence of new products.


Preparation of natural fragrances by green extraction technology


Low temperature extraction technology is a modern extraction technology that mainly combines the principle of shear force, vibration force effect and similarity compatibility effect to extract flavor components or plant active components from natural plant resources. It integrates supercritical fluid extraction, ultrasonic extraction, microwave extraction, biological enzyme extraction and other technical advantages, can be adjusted according to the characteristics of raw materials and product requirements, has the advantages of high efficiency, green environmental protection, safety and ensure the activity of active ingredients and aroma, a wide range of applications, low operating temperature.


Preparation of natural fragrances by high efficiency chromatography


Efficient chromatography separation technology mainly according to the different characteristics of components, such as polarity, adsorption, solubility, the shape and size of molecules, molecules of charge and affinity and other aspects of the difference of repeated distribution and to separate a physical separation technology. It has the advantages of not destroying the activity and aroma of the active ingredients, easy operation and easy amplification, and has shown a broad market prospect. Bolton has a variety of different specifications of chromatography equipment, can meet the small test, pilot test and scale up production and other different requirements, and has many years of production technology precipitation and experience accumulation.


Preparation of natural spices by low temperature enrichment and purification technology


Low temperature enrichment and purification technology can improve the purity of effective components and shape the product state according to different free path and boiling point of molecules. Bolton has currently include continuous short-range molecular distillation technology, freeze drying technology, low temperature membrane enrichment technology, etc, according to the different requirements of customers for the enrichment and purification of related products, in the current pursuit of natural, the trend of the technology can provide a more close to natural, no add flavors and plant extracts products.


Active high-throughput screening and efficacy evaluation platform


Burton Fragrance has established an active high-throughput screening platform, which can utilize multi-site reaction and optical detection technology to carry out large-scale active ingredient screening, further improve the extraction and separation efficiency of target active ingredients, and contribute to the rapid development of characteristic natural flavor and plant extract products. At the same time, the efficacy evaluation system including in vitro, in vivo and cell models was established to comprehensively evaluate the natural flavor and plant extract products and determine their application scope and use method. Can provide customers with more comprehensive product technical support. At present, the efficacy evaluation items cover more than 20 efficacy items in the fields of personal care products, washing products, fragrances, health food, etc.


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